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A Tradition of Innovation



EDAP TMS: History and Innovations in Prostate Tissue Ablation and Treatment of Urinary Stones

Since it was founded in 1979, EDAP TMS has been committed to introducing new and innovative technologies for a minimally-invasive approach to treating urological disorders. These proprietary technologies, such as Focused Ultrasound or Piezo-electric shock waves, have yielded new minimally-invasive procedures for the treatment of several pathologies such as benign prostatic hyperplasia, localized prostate cancer or urinary tract stones. EDAP TMS's design philosophy is to develop minimally-invasive devices for the benefit of the patient associating treatment efficacy and safety. The strength of EDAP TMS Research and Development activity is to master mechanical, acoustic, electronic and IT technologies to produce state-of-the-art and ergonomic medical devices.

History & Innovations

EDAP TMS products are alternatives to traditional surgical procedures which often involve high costs, significant side effects and long recovery times. Founded in 1979, the Company EDAP originally specialized in the manufacturing and distribution of ultrasound scanners and produced the first piezo-electric lithotripter in 1985. Following a merger with Technomed International S.A. in 1994, EDAP TMS launched various generations of lithotripters, urological laser and Prostate Hyperplasia treatment devices (Prostatron) using TUMT (TransUrethral Microwave Therapy) while developing HIFU technology to treat Prostate Cancer. Today, the core business of EDAP TMS is backed by a solid portfolio of patents and innovations in both ESWL and HIFU technologies.

40 years of innovation in non-invasive Therapies

By constantly investing in R&D, and by partnering with renowned medical research institutions (basic research and clinical research) EDAP TMS has developed a large patent portfolio based on its innovative technologies. The company annually invests 10% of its revenues in Research & Development activities (R&D) to maintain and strengthen its level of innovation and research. EDAP TMS develops innovate projects with the financial support of institutional partners such as, Agence National de la Recherche, BPI France, the DIRECCTE, the Grand Lyon, the Auvergne Rhône-Alpes region.


In the United States, EDAP’s HIFU devices are indicated for the ablation of prostate tissue


HIFU innovations

2018 - Focal One receives FDA clearance

Focal One® is cleared by the U.S. Food and Drug Administration (FDA) for the ablation of prostate tissue.

2017 - Ablatherm Fusion

Ablatherm® Fusion is cleared by the U.S Food and Drug Administration (FDA) for the ablation of prostate tissue.

2017 - CMS reimbursement code for HIFU ablation

The Centers for Medicare and Medicaid Services (CMS) creates a reimbursement C-code for Medicare patients undergoing the Ablatherm® HIFU procedure.

2015 - Ablatherm HIFU receives FDA clearance

Ablatherm® Robotic HIFU is cleared by the U.S. Food and Drug Administration (FDA) for the ablation of prostate tissue.

2013 - Focal One

Image innovationFocal One® is. launched upon CE mark approval. It combines elastic fusion with MRI together with a new Dynamic Focusing HIFU probe and Contrast-Enhanced Ultrasound in order to provide the optimal tool for focal therapy of Prostate Cancer.

2005 - Ablatherm HIFU Integrated Imaging

Ablatherm® HIFU Integrated Imaging is launched. The probe integrates both imaging and treatment transducers.

2000 - Ablapak

Disposable kit patent.

1999-2000 - CE Mark

Ablatherm® HIFU receives the CE mark and industrial production starts.

1999 - Ablasonic

Patent covering Ablasonic® cooling and ultrasound-wave transmitting fluid.

1996 - Ablatherm Multicenter clinical trial

The first multicenter study on Ablatherm® HIFU is launched.

1994 - Patient protection

Patent covering rectal wall monitoring function.

1993 - First prostate cancer treatment

Ablatherm® HIFU is used for the first prostate cancer treatment on men (prototype device).

1991 - Ablatherm

Ablatherm MaxisPatent on Ablatherm® transducer design covering geometry and materials.

1989 - HIFU technology

EDAP TMS and INSERM jointly develop HIFU technology
ESWL innovations

2010 - Visio-Track

Visio-TrackIntroduced with the launch of the Sonolith® i-move, the Visio-Track system allows a freeline ultrasound localization and tracking for a reduced radiation dose during ESWL treatments.

2007 - Stone Locking System

Stone Locking systemIntroduced with the launch of Sonolith® i-sys, the Stone Locking system allows the automatic positioning of the shockwave source on the target based on the X-Ray or Ultrasound image.

1994 - Electroconductive Technology

ElectrodeEDAP TMS and INSERM jointly develop the patented Electroconductive technology for Sonolith® lithotripters.

1990 - Hydrophone

Sonolith® hydrophone patent covering pressure regulation technology on ESWL shock-wave generators.

1986 - Ultrasound Imaging Arm

First ultrasound imaging navigator for ESWL (ultrasound imaging arm) on the Sonolith® 2000.

1985 - Sonolith 2000

Sonolith 3000Cooperation between EDAP TMS and the INSERM (French Institute of Medical Research) leading to the development of the Sonolith® 2000 equipped with a conventional electrohydraulic generator.

1984 - Sonolith LT01

Piezo-electric lithotripsy with in-line sonography (LT01).


[1] In the US, EDAP’s HIFU devices are cleared for the ablation of prostate tissue